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Association Between PIP4K2A Polymorphisms and Acute Lymphoblastic Leukemia Susceptibility

Fei Liao1, Dandan Yin, Yan Zhang

  • 1From the Department of Laboratory Medicine (FL, DY, QH, ZZ, LY, YS, HX), National Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Department of Thoracic Oncology and Cancer Center (YZ), West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China; and Department of Oncology (YL), The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, China.

Medicine
|May 6, 2016
PubMed
Summary

This study confirms that specific single-nucleotide polymorphisms (SNPs) in the PIP4K2A gene are associated with childhood acute lymphoblastic leukemia (ALL) risk. These findings enhance our understanding of genetic factors contributing to ALL development.

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