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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Related Experiment Video

Updated: Mar 21, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
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[RHEUTMATIC MYALGIA COMPLICATED BY AA-AMYLOIDOSIS].

M L Zubkin, Yu V Ovchinnikov, N F Frolova

    Klinicheskaia Meditsina
    |May 7, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Rheumatic myalgia rarely causes AA-amyloidosis, with only 12 cases reported globally. This article details the first documented case in Russia, highlighting a rare complication of this inflammatory condition.

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    Area of Science:

    • Rheumatology
    • Nephrology
    • Pathology

    Background:

    • Rheumatic myalgia is characterized by significant inflammation.
    • AA-amyloidosis is a rare complication, particularly in rheumatic diseases.
    • Giant cell arteritis is often associated with previously reported cases.

    Observation:

    • This study presents the first reported case of rheumatic myalgia complicated by AA-amyloidosis in Russia.
    • The patient's presentation and diagnostic journey are detailed.
    • The case adds to the limited global understanding of this specific complication.

    Findings:

    • Rheumatic myalgia, while inflammatory, shows an exceptionally low incidence of AA-amyloidosis.
    • The rarity of this complication underscores unique pathophysiological aspects.
    • This case contributes valuable data to the scarce literature.

    Implications:

    • Highlights the importance of considering rare complications in inflammatory conditions.
    • May prompt further research into the mechanisms underlying AA-amyloidosis in rheumatic myalgia.
    • Provides crucial clinical data for Russian medical practitioners and researchers.