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Published on: June 23, 2019
Medicinal Attributes of Imidazo[1,2-a]pyridine Derivatives: An Update
Nisha Devi, Dharmender Singh, Ravindra K Rawal
1Department of Chemistry, Dr B R Ambedkar National Institute of Technology, Jalandhar 144011, India. singhv@nitj.ac.in.
Abstract:
The imidazo[1,2-a]pyridine scaffold is recognized as a privileged structure as it represents a promising area for identification of lead structures towards the discovery of new synthetic drug molecules. Several commercial drugs such as Zolpidem, Olprinone, Soraprazan and many other compounds in biological testing and preclinical evaluation, illustrate the wide therapeutic spectrum in this class of drug scaffolds. The present manuscript represents the assimilation of literature pertaining to medicinal aspects of this pharmacophore including the structure-activity relationships.
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