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Related Experiment Videos

Microrecanalization after vasectomy in man.

M J Freund1, J E Weidmann, M Goldstein

  • 1Research Division University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Camden 08103.

Journal of Andrology
|March 1, 1989
PubMed
Summary
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Microrecanalization, small channels in the vas deferens, were found in most vasectomized men. These channels may explain how the testis remains protected and sperm production continues after vasectomy.

Area of Science:

  • Urology
  • Reproductive Biology
  • Surgical Pathology

Background:

  • Spermatozoa have been observed in semen of vasectomized men years after the procedure.
  • The term "microrecanalization" was proposed to describe the morphologic basis for this finding.

Purpose of the Study:

  • To investigate the presence and characteristics of microrecanalization in post-vasectomy specimens.
  • To determine the histological features and extent of microcanals.

Main Methods:

  • Examination of serial sections (5 μm at 200 μm intervals) of 40 vasovasostomy specimens from 20 men (2-14 years postvasectomy).
  • Computerized image analysis to trace microcanal continuity.

Main Results:

  • Microcanals were identified in 27 of 40 specimens (18 men).
Keywords:
BiologyEquipment And SuppliesExaminations And DiagnosesFamily PlanningGenitaliaGenitalia, MaleHistologyLaboratory Examinations And DiagnosesMale SterilizationPhysiologyRecanalizationSemen--analysisSeminal VesiclesSterilization, SexualSurgical EquipmentUrogenital SystemVasectomy

Related Experiment Videos

  • Spermatozoa or sperm heads were found within microcanals in 9 of these 27 specimens.
  • Microcanals were observed in various tissue types and vas deferens segments, independent of the vas deferens' presence.
  • Microcanal continuity ranged from 200 to 1140 μm.
  • Microrecanalization was histologically distinct from inflammation, sperm granuloma, or vasitis nodes.

    • Conclusions:

    • Microrecanalization is a common histological finding in vasectomized men.
    • This phenomenon provides a morphologic and physiological basis for testicular protection and sustained spermatogenesis post-vasectomy.