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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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Design of structurally distinct proteins using strategies inspired by evolution

T M Jacobs1, B Williams2, T Williams2

  • 1Program in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|May 7, 2016
PubMed
Summary

Scientists created a new computational method, SEWING, to build novel proteins by combining existing protein structures. This technique generates diverse, stable protein scaffolds with unique features, advancing protein design capabilities.

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