Related Experiment Video
Updated: Mar 21, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Identifying existing Choosing Wisely recommendations of high relevance and importance to hematology
Lisa K Hicks1, Anita Rajasekhar2, Harriet Bering3
1St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Insights
The American Society of Hematology identified 10 key Choosing Wisely recommendations relevant to blood disorder patients. These focus on reducing unnecessary tests and treatments, promoting value-based care.
Area of Science:
- Medical Stewardship
- Hematology
- Health Policy
Background:
- Choosing Wisely (CW) is a national initiative promoting physician-patient dialogue on unnecessary medical tests and procedures.
- The American Society of Hematology (ASH) sought to identify high-value CW recommendations for hematology patients.
Purpose of the Study:
- To develop and apply a method for identifying and prioritizing Choosing Wisely recommendations from other medical societies relevant to hematology.
- To assess the relevance and importance of existing CW recommendations for patients with blood disorders.
Main Methods:
- Reviewed all 380 available Choosing Wisely recommendations.
- Assessed relevance using the MORE(TM) scale and importance based on six principles (harm avoidance, evidence, cost, relevance, frequency, impact).
- Prioritized recommendations with high relevance and importance to hematology.
Main Results:
- Identified 10 highly relevant and important Choosing Wisely recommendations.
- Key recommendations focused on reducing unnecessary imaging, laboratory tests, treatments, and transfusions.
- Emphasized increasing interdisciplinary collaboration and considering treatment value.
Conclusions:
- The ASH CW Task Force successfully identified crucial recommendations for hematology.
- The developed methodology is adaptable for other medical societies to curate relevant CW guidelines.
- Promoting value-based care and reducing unnecessary interventions are vital in hematology.
Abstract:
Choosing Wisely (CW) is a medical stewardship initiative led by the American Board of Internal Medicine Foundation in collaboration with professional medical societies in the United States. In an effort to learn from and leverage the work of others, the American Society of Hematology CW Task Force developed a method to identify and prioritize CW recommendations from other medical societies of high relevance and importance to patients with blood disorders and their physicians. All 380 CW recommendations were reviewed and assessed for relevance and importance. Relevance was assessed using the MORE(TM) relevance scale. Importance was assessed with regard to six guiding principles: harm avoidance, evidence, aggregate cost, relevance, frequency and impact. Harm avoidance was considered the most important principle. Ten highly relevant and important recommendations were identified from a variety of professional societies. Recommendations focused on decreasing unnecessary imaging, blood work, treatments and transfusions, as well as on increasing collaboration across disciplines and considering value when recommending treatments. Many CW recommendations have relevance beyond the society of origin. The methods developed by the ASH CW Task Force could be easily adapted by other Societies to identify additional CW recommendations of relevance and importance to their fields. Am. J. Hematol. 91:787-792, 2016. © 2016 Wiley Periodicals, Inc.
More Related Videos
05:35Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
Published on: January 19, 2024
08:44An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices
Published on: August 21, 2020
Related Concept Videos
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Hematopoiesis
Regulation of Hematopoietic Stem Cells
Overview of Hematopoiesis
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Lineage Commitment