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RNA-seq

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases.
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...

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Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

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Open-source guideseq software for analysis of GUIDE-seq data

Shengdar Q Tsai^1,2,3,4, Ved V Topkar^1,2,3, J Keith Joung^1,2,3,4

¹Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

Nature Biotechnology

|May 7, 2016

Summary

No abstract available in PubMed .

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