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Related Concept Videos

Ultrasonography01:17

Ultrasonography

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Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
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Related Experiment Video

Updated: Mar 21, 2026

Focused Ultrasound Neuromodulation of Human In Vitro Neural Cultures in Multi-Well Microelectrode Arrays
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Ultrasonic neuromodulation.

Omer Naor1, Steve Krupa, Shy Shoham

  • 1Department of Biomedical Engineering, The Technion-Israel Institute of Technology Haifa 32000, Israel. The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91220, Israel.

Journal of Neural Engineering
|May 7, 2016
PubMed
Summary
This summary is machine-generated.

Ultrasonic waves offer non-invasive neural modulation, exciting or suppressing brain activity. This review covers the physics, engineering, and history of ultrasound

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Area of Science:

  • Neuroscience
  • Biophysics
  • Biomedical Engineering

Background:

  • Ultrasonic waves can be precisely focused for non-invasive neuromodulation.
  • Decades of research have explored ultrasonic neuro-modulation, with recent advances in direct neural excitation and suppression.
  • Applications span from rodent models to human studies.

Purpose of the Study:

  • To provide a comprehensive review of ultrasonic neuromodulation.
  • To cover the physics, engineering, and scientific aspects of ultrasonic fields and their control.
  • To discuss historical foundations and recent findings in the field.

Main Methods:

  • Review of existing literature on ultrasonic neuromodulation.
  • Analysis of the physics and engineering principles of ultrasonic field control.
  • Survey of experimental observations and theoretical models.

Main Results:

  • Ultrasonic waves can be steered and focused non-invasively.
  • Direct neural excitation and suppression have been experimentally observed.
  • Key constraints and engineering solutions for ultrasonic neuromodulation are identified.

Conclusions:

  • Ultrasonic neuromodulation holds significant potential for neural science and engineering.
  • Emerging research directions and clinical applications are highlighted.
  • The field is rapidly advancing with new discoveries and technological developments.