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Related Experiment Videos

Ultraviolet A sunscreen evaluations in normal subjects.

J W Stanfield1, P A Feldt, E S Csortan

  • 1Bristol-Myers Pharmaceutical Research & Development, Buffalo, NY 14213.

Journal of the American Academy of Dermatology
|May 1, 1989
PubMed
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This study demonstrates a new method for testing sunscreen's Ultraviolet A (UVA) protection factor (APF). The modified solar simulator efficiently measures UVA protection, crucial for preventing sun damage.

Area of Science:

  • Dermatology
  • Photobiology
  • Cosmetic Science

Background:

  • Ultraviolet A (UVA) radiation contributes to skin aging and damage.
  • Accurate measurement of UVA protection factor (APF) is essential for sunscreen efficacy.
  • Existing methods for APF determination can be time-consuming or lack standardization.

Purpose of the Study:

  • To evaluate the efficacy of a novel, modified xenon arc solar simulator for determining sunscreen APF.
  • To assess the impact of varying irradiance levels and evaluation times on APF measurements.
  • To establish a convenient and reliable method for quantifying UVA protection in sunscreen formulations.

Main Methods:

  • A modified xenon arc solar simulator was used to administer controlled UVA doses to human skin.

Related Experiment Videos

  • Sunscreen-protected and unprotected skin sites were exposed to UVA at 50 mW/cm² and 100 mW/cm².
  • Erythemal responses were assessed at approximately 5 and 24 hours post-exposure to determine the Minimal Erythema Dose (MED) and APF.

    • Main Results:

    • The mean unprotected UVA MED was 23.6 J/cm² (SD = 4.8).
    • The mean UVA Protection Factor (APF) for the research sunscreen was 3.2 (SD = 0.78).
    • Neither UVA irradiance nor post-exposure evaluation time significantly influenced the MED or APF values.

    Conclusions:

    • The modified solar simulator provides a convenient method for assessing sunscreen APF.
    • The findings suggest that APF measurements are robust across different irradiance levels and evaluation times.
    • This technology aids in the development of effective UVA-protective sunscreens, complementing traditional SPF testing.