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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Railway track-like dermatitis: an atypical Mondor's disease?
F G Aloi1, C F Tomasini, A Molinero
1Department of Dermatology, University of Turin, Italy.
Journal of the American Academy of Dermatology
|May 1, 1989
Summary
Two patients presented with atypical Mondor's disease, characterized by chest wall lesions. Histology revealed eosinophilic infiltrates and collagen degeneration, aiding differential diagnosis.
Area of Science:
- Dermatology
- Pathology
Background:
- Mondor's disease, or sclerosing periphlebitis, typically affects superficial veins.
- Atypical presentations require careful diagnostic consideration.
Observation:
- Two cases of linear, cordlike lesions on the anterolateral chest wall were observed.
- Clinical diagnosis suggested Mondor's disease with unusual features.
Findings:
- Histopathological examination revealed diffuse dermal infiltrate.
- Predominant cells were eosinophils, mixed with lymphocytes and histiocytes.
- Evidence of collagen degeneration was noted, without flame figures.
Implications:
- The findings highlight the importance of considering atypical Mondor's disease.
- Histopathological analysis is crucial for differentiating from other conditions.
- Understanding eosinophilic infiltrates in this context may refine diagnostic criteria.
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