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Related Experiment Video

Updated: Mar 21, 2026

Monitoring the Cancer-Immunity Cycle and Exploring Tumor Microenvironment Dynamics
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Monitoring the Cancer-Immunity Cycle and Exploring Tumor Microenvironment Dynamics

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From inflammation to cancer.

A Korniluk1, O Koper1, H Kemona1

  • 1Department of Clinical Laboratory Diagnostics, Medical University of Bialystok, Ul. Waszyngtona 15A, 15-276, Bialystok, Poland.

Irish Journal of Medical Science
|May 9, 2016
PubMed
Summary

Inflammation

Keywords:
Acute inflammationAdhesion moleculesCancerChronic inflammation

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Area of Science:

  • Oncology
  • Immunology

Background:

  • The link between inflammation and cancer progression has been a long-standing research topic.
  • Historical evidence suggests acute inflammation may inhibit cancer, while chronic inflammation promotes it.

Purpose of the Study:

  • To explore the historical discovery and mechanisms linking acute and chronic inflammation to cancer.
  • To understand the role of inflammation in cancer development and progression.

Main Methods:

  • Review of historical scientific evidence.
  • Analysis of shared mechanisms between inflammation and cancer, including cell proliferation and angiogenesis.

Main Results:

  • Inflammation and cancer share common developmental pathways like cell proliferation and angiogenesis.
  • Chronic inflammatory cells and factors within the tumor microenvironment accelerate tumor growth and inhibit apoptosis.

Conclusions:

  • This article provides a historical overview of the discovery of inflammation-cancer links.
  • It details the mechanisms and potential connections between acute/chronic inflammation and cancer progression.