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Synovial Sarcoma in a Neonate.

Venkatraman Radhakrishnan1, Anjana Joel, Shirley Sundersingh

  • 1Departments of Medical Oncology, *Pathology and #Surgical Oncology, Cancer Institute, Adyar, Chennai, India. Correspondence to: Dr Venkatraman Radhakrishnan, Associate Professor, Department of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai 600 020, India. venkymd@gmail.com.

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|May 10, 2016
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Summary
This summary is machine-generated.

Neonatal tumors are rare, but this case highlights synovial sarcoma in a 3-day-old infant. Early diagnosis and multi-modal treatment led to a positive outcome with no disease recurrence after 12 months.

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Area of Science:

  • Pediatric Oncology
  • Molecular Pathology

Background:

  • Malignant tumors are exceptionally rare in neonates.
  • Synovial sarcoma, a soft tissue sarcoma, typically affects adolescents and young adults.

Observation:

  • A 3-day-old neonate presented with a tumor in the left biceps.
  • Diagnostic procedures included tumor biopsy and molecular analysis.

Findings:

  • The tumor was confirmed as synovial sarcoma through histopathology and molecular studies.
  • The neonate received a comprehensive treatment regimen involving surgery and chemotherapy.

Implications:

  • This case demonstrates that synovial sarcoma can occur in the neonatal period.
  • Early detection and aggressive multi-modal therapy are crucial for managing rare neonatal soft tissue sarcomas.