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Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation
Published on: August 21, 2019
Impacts of complex behavioral responses on asymmetric interacting spreading dynamics in multiplex networks
Quan-Hui Liu1,2, Wei Wang1,2, Ming Tang1,2
1Web Sciences Center, University of Electronic Science and Technology of China, Chengdu 611731, China.
Abstract:
Information diffusion and disease spreading in communication-contact layered network are typically asymmetrically coupled with each other, in which disease spreading can be significantly affected by the way an individual being aware of disease responds to the disease. Many recent studies have demonstrated that human behavioral adoption is a complex and non-Markovian process, where the probability of behavior adoption is dependent on the cumulative times of information received and the social reinforcement effect of the cumulative information. In this paper, the impacts of such a non-Markovian vaccination adoption behavior on the epidemic dynamics and the control effects are explored. It is found that this complex adoption behavior in the communication layer can significantly enhance the epidemic threshold and reduce the final infection rate. By defining the social cost as the total cost of vaccination and treatment, it can be seen that there exists an optimal social reinforcement effect and optimal information transmission rate allowing the minimal social cost. Moreover, a mean-field theory is developed to verify the correctness of simulation results.
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