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PET, CT, and MR Imaging for Assessment of Thoracic Malignancy: Structure Meets Function
Sharyn Katz1, Thomas Ferrara1, Abass Alavi1
1Department of Radiology, Hospital of the University of Pennsylvania, School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Multimodality imaging is key for thoracic malignancy. [18F]-2-fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography (PET)/CT is increasingly used, offering advantages over PET-only scans for patient evaluation.
Area of Science:
- Radiology
- Nuclear Medicine
- Oncology
Background:
- Multimodality imaging is essential for diagnosing and managing thoracic malignancies.
- Computed Tomography (CT) is a cornerstone for staging and restaging.
- Positron Emission Tomography (PET) and Magnetic Resonance (MR) imaging offer complementary information.
Purpose of the Study:
- To review the role of various imaging modalities in thoracic malignancy.
- To highlight the growing importance of FDG-PET/CT in clinical practice.
- To discuss the potential future applications of PET/MR imaging.
Main Methods:
- Review of current imaging techniques for thoracic cancers.
- Emphasis on the integration of CT and FDG-PET.
- Discussion of the utility of MR imaging and emerging PET/MR.
Main Results:
- CT is central for staging, but FDG-PET/CT enhances diagnostic accuracy.
- [18F]-2-fluoro-2-deoxy-D-glucose (FDG)-PET/CT is becoming the standard, replacing PET-only imaging.
- MR imaging aids in specific staging and characterization scenarios.
Conclusions:
- FDG-PET/CT is a powerful tool in the comprehensive evaluation of thoracic malignancies.
- The combination of modalities optimizes patient management.
- PET/MR imaging may offer future advancements in the field.
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