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Related Experiment Video

Updated: Mar 21, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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Vascular access in critical limb ischemia.

Won Yu Kang1, Umberto Campia1, Hideaki Ota1

  • 1Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|May 10, 2016
PubMed
Summary

Percutaneous endovascular intervention is a leading treatment for critical limb ischemia. Understanding various arterial access routes is key to improving patient outcomes in severe peripheral arterial disease.

Keywords:
AmputationAntegrade accessCritical limb ischemiaLimb salvageMetatarsalPedalRetrograde accessVascular access

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Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Peripheral Arterial Disease

Background:

  • Percutaneous endovascular intervention is a primary treatment for critical limb ischemia.
  • Technological advancements have made it comparable to bypass surgery in limb salvage rates, with fewer complications.

Purpose of the Study:

  • To review arterial access routes for percutaneous intervention in critical limb ischemia.
  • To discuss the advantages, disadvantages, and clinical outcomes of each approach.

Main Methods:

  • Review of current literature on percutaneous endovascular intervention for critical limb ischemia.
  • Analysis of various arterial access sites, including antegrade and retrograde approaches.

Main Results:

  • Multiple arterial access routes are available, offering flexibility for interventionalists.
  • The choice of access site significantly impacts the success of percutaneous intervention.

Conclusions:

  • Optimizing the selection of arterial access routes can enhance clinical outcomes for patients with critical limb ischemia.
  • Understanding the nuances of each approach is crucial for interventionalists.