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Updated: Mar 21, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Application of Advanced MR Imaging Techniques and the Evolving Role of PET/MR Imaging in Neuro-oncology
Thomas C Kwee1, Maarten L Donswijk1
1Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.
Abstract:
A requisite to achieve a better outcome in patients with high-grade glioma is the development of noninvasive imaging techniques that improve tumor detection, delineation, and grading, before, during, and after therapy. This article reviews the value of a selection of important advanced MR imaging techniques (diffusion-weighted MR imaging, diffusion-tensor imaging, perfusion MR imaging, and MR spectroscopy) and the evolving role of positron emission tomography (PET)/MR imaging in the evaluation of high-grade gliomas in various settings. This review introduces the reader to the basic principles and clinical applications of these advanced MR imaging and PET/MR imaging techniques.
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