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Published on: December 13, 2024
Data on glycerol/tartaric acid-based copolymer containing ciprofloxacin for wound healing applications
E De Giglio1, M A Bonifacio1, S Cometa2
1Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, 70126 Bari, Italy.
Abstract:
This data article is related to our recently published research paper "Exploiting a new glycerol-based copolymer as a route to wound healing: synthesis, characterization and biocompatibility assessment", De Giglio et al. (Colloids and Surfaces B: Biointerfaces 136 (2015) 600-611) [1]. The latter described a new copolymer derived from glycerol and tartaric acid (PGT). Herein, an investigation about the PGT-ciprofloxacin (CIP) interactions by means of Fourier Transform Infrared Spectroscopy (FT-IR) acquired in Attenuated Total Reflectance (ATR) mode and Differential Scanning Calorimetry (DSC) was reported. Moreover, CIP release experiments on CIP-PGT patches were performed by High Performance Liquid Chromatography (HPLC) at different pH values.

