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Related Experiment Video

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Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
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Allergy and laryngeal disorders.

John H Krouse1

  • 1Department of Otolaryngology - Head and Neck Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.

Current Opinion in Otolaryngology & Head and Neck Surgery
|May 10, 2016
PubMed
Summary

Allergy may trigger laryngeal inflammation and symptoms in some individuals. Research suggests a link between allergies and laryngeal conditions, with sticky secretions being a potential indicator of allergic laryngitis.

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Area of Science:

  • Otolaryngology
  • Allergy and Immunology
  • Laryngology

Background:

  • Allergic laryngitis has garnered sustained research interest over the past 15 years.
  • Epidemiological and experimental studies have refined the understanding of its nature and clinical presentation.

Purpose of the Study:

  • To review recent literature on allergic laryngitis.
  • To clarify the relationship between allergy and laryngeal symptoms.

Main Methods:

  • Review of recent epidemiological and experimental studies.
  • Analysis of findings related to laryngeal symptoms, objective signs, and endoscopic examinations.
  • Examination of experimental interventions in animal and human models.

Main Results:

  • Epidemiological studies show a significant association between allergy and laryngeal symptoms/signs.
  • Recent research questions the reliability of endoscopic examinations for diagnosing laryngopharyngeal reflux.
  • Sticky, thick endolaryngeal secretions are linked to allergic laryngitis.
  • Experimental data suggest a potential direct causal role for allergy in some cases.

Conclusions:

  • Allergy is a plausible trigger and causative factor for laryngeal inflammation and symptoms in certain individuals.
  • Further research is needed to fully characterize allergic laryngitis and establish diagnostic protocols.