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Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
Published on: November 4, 2022
Intradural Extramedullary Spinal Cord Metastasis of the Prostate: A Case Presentation and Review of the Literature
Amparo Wolf1, Ryan Johnstone1, Fawaz Siddiqi1
1Department of Clinical Neurological Sciences,Division of Neurosurgery,Schulich School of Medicine and Dentistry,University of Western Ontario,London,Ontario,Canada.
Abstract:
Prostate cancer is associated with vertebral metastasis in up to 10% of patients; however, intradural spinal cord metastases (ISCM) are much less frequent. We present the clinical and histopathological findings of a patient with ISCM arising from prostate. A PubMed literature search for ISCM from the prostate yielded a total of nine additional cases. ISCM of the prostate occurs at a late stage of systemic disease and the prognosis is generally poor. Decompressive surgery followed by adjuvant radiation therapy may help reduce intractable pain and stabilize neurological symptoms, thereby improving quality of life.
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