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Updated: Mar 21, 2026

Techniques to Induce and Quantify Cellular Senescence
Published on: May 1, 2017
RETRACTED: USP1 Regulates Cellular Senescence by Controlling Genomic Integrity
Müge Ogrunc1, Ricardo Ivan Martinez-Zamudio2, Paul Ben Sadoun3
1Institut Pasteur, Laboratory of Nuclear Organization and Oncogenesis, Department of Cell Biology and Infection, 75015 Paris, France; INSERM, U993, 75015 Paris, France; Equipe Labellisée Ligue Nationale Contre le Cancer, 14 rue Corvisart, 75013 Paris, France.
Abstract:
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors. We, the authors, were made aware of irregularities associated in western blots shown in our article. We have further investigated the matter and found that the paper contains multiple examples of incorrect data use and image flipping in four figures, including the vertical flipping and reuse of the panel in Figures 1B and 3D, similar flipping and incorrect blot image in Figure 2C, and incorrect data use in Figure 4A. All of these figures were assembled by the corresponding author (O.B.) who takes full responsibility for the inaccuracies. Under these circumstances, we believe that the most responsible course of action is to retract the paper. We sincerely apologize to the scientific community for any inconvenience resulting from the publication and retraction of this manuscript.
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