Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Scale-Up Processes

Scale-Up Processes

The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...

Population Growth

Population Growth

Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.

Modeling with Differential Equations

Modeling with Differential Equations

Population dynamics can be described mathematically by considering the population size P(t) as a function of time. The rate of change of the population is then represented by the derivative of P(t). A simple assumption is that the rate of growth is proportional to the size of the population itself. This leads to an exponential growth model, where the population increases rapidly without bound. While this is a useful first approximation, it does not reflect realistic long-term...

Exponential Equations for Modeling Growth

Exponential Equations for Modeling Growth

Exponential models are essential for describing rapid, multiplicative changes in natural systems, such as population growth. When a population doubles at regular intervals, the process can be modeled using a suitable base. For instance, a bacterial culture that doubles every three hours follows the model n(t)=n0⋅2t/3, where n(t) is the population at the time t.A more general model uses the natural base e, especially for continuous growth. This takes the form n(t)=n0⋅ert, where r is...

Exponential Equations with Logarithms: Problem Solving

Exponential Equations with Logarithms: Problem Solving

In ecological studies, exponential models are often used to predict how populations grow over time under favorable conditions. These models assume that the growth rate is proportional to the current population, leading to continuous and compounding increases.The model expresses the population as a function of time, combining the initial population with a growth factor raised to an exponent involving the growth rate and time. To estimate how long it takes for a population to reach a specific...

Scaling

Scaling

In designing and analyzing filters, resonant circuits, or circuit analysis at large, working with standard element values like 1 ohm, 1 henry, or 1 farad can be convenient before scaling these values to more realistic figures. This approach is widely utilized by not employing realistic element values in numerous examples and problems; it simplifies mastering circuit analysis through convenient component values. The complexity of calculations is thereby reduced, with the understanding that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Community-engaged design of a virtual diabetes prevention program intervention with care coordination.

BMC health services research·2026

Same author

Virtual delivery of evidence-based, person-centered breastfeeding peer counseling: a qualitative evaluation of women's experiences and perceptions.

International breastfeeding journal·2026

Same author

Effective Implementation Strategies for Delivering Nutritional Interventions through the Health System to Prevent Malnutrition during Pregnancy: A Systematic Review and Meta-analysis.

Advances in nutrition (Bethesda, Md.)·2026

Same author

Nutritional assessment and lifestyle counseling for pregnant women in primary health care units in Mexico: implementation evaluation.

BMC primary care·2026

Same author

The impact of the United States' distancing from the UN and withholding WHO funding on maternal and child health and nutrition in the Latin America & Caribbean region.

International journal for equity in health·2026

Same author

Lactation Newsmakers - Dr. Rafael Perez-Escamilla's Academic and Professional Journey: Advancing Global Breastfeeding Through Science and Policy.

Journal of human lactation : official journal of International Lactation Consultant Association·2026

Search research articles

Related Experiment Video

Updated: Mar 21, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

Published on: September 22, 2023

Scaling up breastfeeding programmes in a complex adaptive world.

Rafael Pérez-Escamilla¹, Victoria Hall Moran²

¹Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.

Maternal & Child Nutrition

|May 11, 2016

Summary

This summary is machine-generated.

Optimal breastfeeding offers significant global health benefits but remains underutilized. Scaling up effective national breastfeeding programs requires complex research and decision-making tools for widespread adoption.

More Related Videos

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Published on: February 7, 2025

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Published on: February 5, 2019

Related Experiment Videos

Last Updated: Mar 21, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

Published on: September 22, 2023

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Published on: February 7, 2025

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Published on: February 5, 2019

Area of Science:

Public Health
Maternal and Child Health
Health Policy

Background:

The 2016 Breastfeeding Lancet Series highlights extensive benefits of optimal breastfeeding for child and maternal health, alongside significant public health cost savings.
Despite established evidence, global progress in scaling up effective breastfeeding programs remains limited, indicating a critical gap between knowledge and implementation.

Discussion:

Effective national breastfeeding programs are crucial for increasing exclusive breastfeeding duration, necessitating a global priority for their uptake and scale-up.
Complex systems analysis and longitudinal research are essential to understand how to best support decision-makers in implementing these programs.
Well-validated participatory decision-making tools are needed to assess baseline needs, costs, and scaling-up progress within countries.

Key Insights:

Optimal breastfeeding practices yield substantial health and economic advantages globally.
Underutilization of this knowledge stems from insufficient progress in scaling up effective breastfeeding interventions worldwide.
Empowering decision-makers with appropriate tools is key to achieving widespread adoption of beneficial breastfeeding practices.

Outlook:

The availability of systems thinking frameworks and scaling-up models provides a foundation for future research and implementation.
Prospective research should focus on adapting and replicating successful scaling-up strategies across diverse national contexts.
Continued investment in research and implementation science is vital to overcome barriers and maximize the public health impact of breastfeeding.