[Exacerbation of associated bronchial asthma in patients with myocardial infarct]

During follow-up of 27 patients with previous long-term history of bronchial asthma it has been established that in 7 of them there was aggravation of broncho-pulmonary illness in the late terms of setting in of myocardial infarction (on the 3rd-6th week, or in 30 days, on the average). Typical features in these patients were blood hypereosinophilia reaching 16-24 per cent and parallel development in some of them of clinical manifestations of the postinfarction syndrome such as pericarditis, pleurisy and transitory lung infiltration. It is believed that this spontaneous aggravation of bronchial asthma in late terms of myocardial infarction can be regarded as one of the manifestations of the postinfarction syndrome typical for this clinical condition. Long-action glucocorticoids (metipred) should be prescribed prior to the development of the clinical symptoms of bronchial asthma to this category of patients taking into consideration only the dynamics of blood eosinophil count.