Quantification of clearance and creep in acetabular wear measurements

Mo Saffarini1, Thomas Gregory1, Eric Vandenbussche1

  • 11 Accelerate Innovation Management, Geneva, Switzerland ; 2 Department of Orthopaedic Surgery, Hôpital Européen Georges Pompidou, University René Descartes, Faculty of Medicine, Paris, France ; 3 Department of Mechanical Engineering, Imperial College London, London, UK.

Abstract

Related Concept Videos

Factors Affecting Creep01:28

Factors Affecting Creep

In normal-weight aggregate concrete, the hardened cement paste is the primary contributor to creep, whereas the aggregates, being stiffer than the cement paste, are more resilient to stress-induced deformation. The stiffness of the aggregates is defined by their modulus of elasticity, and the more voluminous they are in the concrete, the less it will creep.
Further, the water/cement ratio is critical, as a lower ratio increases concrete strength, thus reducing creep. The strength of the...
511
Creep in Concrete01:22

Creep in Concrete

Creep refers to the time-dependent increase in strain under a sustained load, excluding other time-dependent deformations associated with shrinkage, swelling, and thermal expansion in concrete. The primary mechanism behind creep involves the loss of physically adsorbed water from the calcium silicate hydrate within the hydrated cement paste. This process is further exacerbated by concrete's non-linear stress-strain relationship, microcrack development in the interfacial transition zone, and...
1.6K
Clearance Models: Noncompartmental Models01:17

Clearance Models: Noncompartmental Models

Clearance is a pharmacokinetic parameter traditionally defined by compartment models, signifying the rate at which a drug is expelled from the body. However, a noncompartmental model offers an alternative method for assessing clearance, primarily employing empirical data obtained after administering a single drug dose.
The noncompartmental approach capitalizes on extensive sampling data, correlating the volume of distribution to systemic exposure and the administered dosage. This method enables...
342