Pharmacy impact on medication reconciliation in the medical intensive care unit

Brittany M Wills1, William Darko2, Robert Seabury2

  • 1Nesbitt School of Pharmacy, Wilkes University, Wilkes-Barre, PA, USA.

Abstract

Insights

Pharmacy medication histories significantly reduced serious medication discrepancies in ICUs. This study highlights the effectiveness of pharmacy-driven medication reconciliation in critical care settings.

Area of Science:

  • Medical Sciences
  • Clinical Pharmacy
  • Patient Safety

Background:

  • Pharmacy-driven medication history (MH) programs are effective in reducing serious or potentially life-threatening (S/PLT) medication discrepancies (MDs) in various healthcare settings.
  • However, their impact in Intensive Care Units (ICUs) has been less established.

Purpose of the Study:

  • To evaluate the effectiveness of pharmacy-driven medication history (MH) programs in reducing S/PLT medication discrepancies (MDs) specifically within an Intensive Care Unit (ICU) setting.
  • To assess the frequency and nature of MDs in patients admitted to the medical ICU.

Main Methods:

  • A 6-week study involving repeated medication histories (MHs).
  • Documentation of patient demographics, number, and nature of medication discrepancies (MDs).
  • Grading of discrepancy severity using a validated method; primary outcome was the proportion of MHs with >1 S/PLT MDs.

Main Results:

  • Sixty-three repeated MHs were analyzed.
  • Pharmacy-led MHs demonstrated a significant reduction in S/PLT MDs, with 0% containing ≥1 S/PLT MDs compared to 50% in non-pharmacy MHs (P < 0.001).

Conclusions:

  • Pharmacy-driven medication histories significantly decreased S/PLT MDs in this sample of ICU patients.
  • Serious medication discrepancies were common upon admission and on home medication lists for ICU patients.
  • Pharmacy-driven medication reconciliation (MR) proved effective in reducing the number and frequency of these critical discrepancies, though further research is needed to optimize MR procedures.

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