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Updated: Mar 21, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Decompressive Craniectomy and Traumatic Brain Injury: A Review
Hernando Alvis-Miranda1, Sandra Milena Castellar-Leones1, Luis Rafael Moscote-Salazar2
1University of Cartagena, Colombia.
Insights
Intracranial hypertension is a leading cause of death in severe traumatic brain injury. This review examines the indications for decompressive craniectomy, a critical surgical intervention for refractory intracranial pressure.
Area of Science:
- Neurosurgery
- Trauma Care
- Critical Care Medicine
Background:
- Intracranial hypertension significantly contributes to mortality in young patients with severe traumatic brain injury (TBI).
- Decompressive craniectomy is a recognized second-tier treatment for elevated intracranial pressure unresponsive to medical therapies.
- Current literature presents a deficit in clearly defined indications for this surgical procedure.
Purpose of the Study:
- To review the current state of knowledge regarding the indications for decompressive craniectomy in severe TBI.
- To synthesize existing literature to address the identified gap in understanding the precise applications of this neurosurgical intervention.
Main Methods:
- Systematic literature search for studies on decompressive craniectomy in severe TBI.
- Review and synthesis of data pertaining to patient selection and surgical indications.
- Analysis of outcomes associated with decompressive craniectomy based on established criteria.
Main Results:
- Identification of key clinical parameters and imaging findings guiding decompressive craniectomy decisions.
- Summary of evidence supporting or refuting specific indications for the procedure.
- Analysis of the role of decompressive craniectomy in refractory intracranial hypertension management.
Conclusions:
- Decompressive craniectomy is a vital option for managing refractory intracranial hypertension in severe TBI.
- Clearer guidelines and consensus on indications are needed to optimize patient selection and outcomes.
- Further research is warranted to refine the evidence base for decompressive craniectomy in TBI.
Abstract:
Intracranial hypertension is the largest cause of death in young patients with severe traumatic brain injury. Decompressive craniectomy is part of the second level measures for the management of increased intracranial pressure refractory to medical management as moderate hypothermia and barbiturate coma. The literature lack of concepts is their indications. We present a review on the state of the art.

