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An antifungal constituent from the stem bark of Butea monosperma
B M Bandara1, N S Kumar, K M Samaranayake
1Department of Chemistry, University of Peradeniya, Sri Lanka.
Journal of Ethnopharmacology
|February 1, 1989
Abstract:
The petroleum and ethyl acetate extracts of the stem bark from Butea monosperma displayed antifungal activity against Cladosporium cladosporioides. The active constituent of low polarity was isolated by bioassay-monitored chromatographic fractionation, and identified as (-)-medicarpin by comparison of physical data. The antifungal activity of (-)-medicarpin was found to be greater than that of Benlate, a standard fungicide, while (-)-medicarpin acetate also exhibited significant activity against C. cladosporiodes.