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H-Type Hypertension and C Reactive Protein in Recurrence of Ischemic Stroke

Qing Zhang1, De-Xing Qiu2, Rong-Li Fu3

  • 1Institute of Public Health, School of Nursing, Henan University, Kaifeng 475004, China. zq71200@163.com.

International Journal of Environmental Research and Public Health
|May 11, 2016
PubMed

Insights

Recurrent ischemic stroke (RIS) is linked to H-type hypertension and elevated C-reactive protein (CRP). Managing these factors may help reduce the risk of stroke recurrence.

Area of Science:

  • Neurology
  • Cardiology
  • Clinical Biochemistry

Background:

  • Hypertension with high homocysteine (H-type hypertension) and elevated C-reactive protein (CRP) are known risk factors for ischemic stroke.
  • The association between H-type hypertension, CRP levels, and recurrent ischemic stroke (RIS) remains unclear.

Purpose of the Study:

  • To investigate the correlation between H-type hypertension and CRP levels with the incidence of recurrent ischemic stroke (RIS).

Main Methods:

  • A cohort of 987 consecutive patients with acute ischemic stroke was analyzed.
  • Demographic, clinical, and biochemical parameters, including CRP and homocysteine (Hcy) levels, were assessed.
  • Multivariate analysis was used to identify independent risk factors for RIS.

Main Results:

  • Among 987 patients, 234 experienced RIS.
  • Elevated CRP levels were found in 38% of RIS patients, and 91.5% had H-type hypertension.
  • Independent risk factors for RIS included older age, male sex, diabetes, H-type hypertension, and elevated CRP levels.

Conclusions:

  • H-type hypertension and elevated CRP levels are significantly associated with an increased risk of recurrent ischemic stroke.
  • Controlling H-type hypertension and CRP levels may be a viable strategy to reduce the incidence of RIS.

Keywords:
C reactive proteinH-type hypertensionrecurrence ischemic stroke

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