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Pragmatic trial design elements showed a different impact on trial interpretation and feasibility than explanatory

Joost B Nieuwenhuis1, Elaine Irving2, Katrien Oude Rengerink1

  • 1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, the Netherlands.

Journal of Clinical Epidemiology
|May 11, 2016
PubMed
Abstract

Keywords:
Explanatory trialGeneralizabilityOperational feasibilityPragmatic clinical trialsPrecisionReal-world evidenceTrial designValidity

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