Related Experiment Video

Updated: Mar 21, 2026

Using Enzyme-based Biosensors to Measure Tonic and Phasic Glutamate in Alzheimer's Mouse Models
10:46

Using Enzyme-based Biosensors to Measure Tonic and Phasic Glutamate in Alzheimer's Mouse Models

Published on: May 3, 2017

11.8K

Glutamate in peripheral organs: Biology and pharmacology

Jie Du1, Xiao-Hui Li2, Yuan-Jian Li2

  • 1Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China.

European Journal of Pharmacology
|May 11, 2016
PubMed

Keywords:
(RS)-1-aminoindan-1,5,dicarboxylic acid (AIDA) (PubChem CID:2071)2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline (NBQX) (PubChem CID: 71312122)2-amino-5-phosphono-valcrate (APV) (PubChem CID: 135342)2-amino-7-phosphonoheptanoate (PubChem CID: 18538056)6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) (PubChem CID: 3721046)Aspirin (PubChem CID:2244)Dextrorphan (PubChem CID: 5360697)Dizocilpine (MK-801) (PubChem CID: 9862634)GYKI52466 (PubChem CID: 3538)Gamma-aminomethyl sulfonate (PubChem CID: 2935)GlutamateGlutamate receptorGlutamate transporterGlutamic acid (PubChem CID:611)Ketamine (PubChem CID: 3821)Kynurenic acid (PubChem CID: 3845)LY367385 (PubChem CID: 5311261)N-methyl-D-aspartate receptor (NMDA receptor)Perampanel (PubChem CID: 9924495)Peripheral tissuesPhencyclidine (PCP) (PubChem CID: 6468)Quisqualate (PubChem CID: 40539)

More Related Videos

Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice08:27

Single Synapse Indicators of Glutamate Release and Uptake in Acute Brain Slices from Normal and Huntington Mice

Published on: March 11, 2020

6.7K
Glutamate and Hypoxia as a Stress Model for the Isolated Perfused Vertebrate Retina07:48

Glutamate and Hypoxia as a Stress Model for the Isolated Perfused Vertebrate Retina

Published on: March 22, 2015

8.3K

Related Concept Videos

Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
4.6K
Antiepileptic Drugs: Glutamate Antagonists01:14

Antiepileptic Drugs: Glutamate Antagonists

Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
1.2K
Ligand-gated Ion Channels01:19

Ligand-gated Ion Channels

Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...
15.3K
Glial Cells01:04

Glial Cells

Overview
96.3K
The Physiology of Taste01:24

The Physiology of Taste

The perception of a salty flavor is facilitated by sodium ions within the oral salivary fluid. Upon consumption of a salty substance, salt crystals disassemble, leading to the liberation of its constituents—Na+ and Cl- ions. These ions subsequently dissolve into the salivary fluid present in the oral cavity. The external environment of the gustatory cells experiences an elevation in Na+ concentration, thereby establishing a potent concentration gradient. This gradient propels the...
8.2K
Drugs Acting on Autonomic Ganglia: Stimulants01:23

Drugs Acting on Autonomic Ganglia: Stimulants


Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
2.2K