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Projection flow imaging by bolus tracking using stimulated echoes.

T K Foo1, W H Perman, C S Poon

  • 1Department of Medical Physics, University of Wisconsin, Madison 53706.

Magnetic Resonance in Medicine
|February 1, 1989
PubMed
Summary
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This study introduces novel planar- and volume-selective stimulated echo methods for enhanced bolus tracking in magnetic resonance imaging. These techniques offer increased sensitivity compared to traditional spin and gradient echo methods.

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Biomedical Engineering
  • Medical Physics

Background:

  • Traditional bolus tracking methods utilize spin echoes or gradient echoes.
  • These existing techniques have limitations in sensitivity and signal acquisition.

Purpose of the Study:

  • To introduce and evaluate two new bolus tracking methods: planar-selective and volume-selective stimulated echoes.
  • To demonstrate the increased sensitivity and improved performance of these novel stimulated echo techniques.

Main Methods:

  • Developed planar-selective stimulated echo technique using selective and nonselective radiofrequency pulses.
  • Developed volume-selective stimulated echo technique for enhanced stationary spin suppression.
  • Employed flow-compensated dephasing gradients to ensure stimulated echo formation and minimize flow dephasing.

Related Experiment Videos

  • Optimized relaxation times (tau 1 and tau 2) to minimize signal loss due to T2 dephasing, particularly in blood.

    • Main Results:

    • The planar-selective method images flowing spins angiographically by exciting spins in a specific plane.
    • The volume-selective method suppresses stationary spins through targeted volume excitation.
    • Both methods demonstrated increased sensitivity compared to conventional spin echo and gradient echo bolus tracking.
    • Signal loss due to T2 dephasing was minimized by keeping tau 1 short, leveraging the T1 >> T2 property of blood.

    Conclusions:

    • Planar- and volume-selective stimulated echo techniques represent advancements in bolus tracking MRI.
    • These novel methods offer superior sensitivity for imaging blood flow and contrast agent dynamics.
    • The techniques provide valuable tools for various clinical and research applications requiring precise bolus tracking.