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Role of Diffusion Weighted Imaging in Musculoskeletal Infections: Current Perspectives
Yogesh Kumar1, Mohammad Khaleel2, Ethan Boothe3
1Department of Radiology, Yale New Haven Health System at Bridgeport Hospital, Bridgeport, CT, USA.
Abstract:
Accurate diagnosis and prompt therapy of musculoskeletal infections are important prognostic factors. In most cases, clinical history, examination and laboratory findings help one make the diagnosis, and routine magnetic resonance imaging (MRI) is useful to identify the extent of the disease process. However, in many situations, a routine MRI may not be specific enough especially if the patient cannot receive contrast intravenously, thereby delaying the appropriate treatment. Diffusion-weighted imaging (DWI) can help in many such situations by providing additional information, accurate characterization and defining the extent of the disease, so that prompt treatment can be initiated. In this article, we illustrate the imaging findings of the spectrum of musculoskeletal infections, emphasizing the role of DWI in this domain.
Key Points:
• Abscess in background cellulitis is detected on DWI. • Infectious tenosynovitis shows diffusion restriction as compared to mechanical tenosynovitis. • Pyomyositis with abscess can be differentiated from diabetic myonecrosis on DWI. • Intraosseous abscess is bright on DWI versus devitalized tissue, sequestrum and air. • DWI can be used to differentiate spine infection from simple Modic changes.
Insights
Diffusion-weighted imaging (DWI) enhances musculoskeletal infection diagnosis when routine MRI is insufficient. DWI provides crucial details for accurate characterization and extent definition, enabling prompt treatment initiation for better patient outcomes.
Area of Science:
- Radiology
- Musculoskeletal Imaging
- Infectious Disease Imaging
Background:
- Accurate diagnosis and prompt therapy are crucial for musculoskeletal infections.
- Routine MRI aids diagnosis but may lack specificity, especially without contrast.
- Delayed treatment due to diagnostic ambiguity can negatively impact prognosis.
Purpose of the Study:
- To illustrate imaging findings of musculoskeletal infections.
- To emphasize the role of Diffusion-weighted imaging (DWI) in diagnosing these infections.
- To highlight DWI's utility when contrast-enhanced MRI is not feasible.
Main Methods:
- Review of imaging findings in musculoskeletal infections.
- Emphasis on the application and interpretation of Diffusion-weighted imaging (DWI).
- Comparison of DWI findings with conventional MRI and clinical data.
Main Results:
- DWI effectively detects abscesses in cellulitis.
- Infectious tenosynovitis demonstrates diffusion restriction compared to mechanical tenosynovitis.
- DWI differentiates pyomyositis with abscess from diabetic myonecrosis.
- Intraosseous abscesses appear bright on DWI, distinguishing them from non-viable tissue or air.
- DWI aids in differentiating spinal infections from Modic changes.
Conclusions:
- Diffusion-weighted imaging (DWI) is a valuable tool for diagnosing musculoskeletal infections.
- DWI provides critical information for accurate characterization and extent assessment.
- The study underscores DWI's importance in guiding prompt and appropriate treatment decisions.
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