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Extracorporeal life support can be a first-line treatment in children with acute fulminant myocarditis

Se Yong Jung1, Hong Ju Shin2, Jo Won Jung1

  • 1Division of Pediatrics, Department of Pediatric Cardiology, Congenital Heart Disease Center, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, South Korea.

Interactive Cardiovascular and Thoracic Surgery
|May 12, 2016
PubMed

Insights

Extracorporeal life support (ECLS) offers excellent survival rates for children with acute fulminant myocarditis. This study found that 92.3% of pediatric patients requiring mechanical circulatory support survived.

Area of Science:

  • Pediatric Cardiology
  • Critical Care Medicine
  • Cardiovascular Surgery

Background:

  • Severe acute myocarditis in children often necessitates mechanical circulatory support.
  • The clinical outcomes for pediatric patients with acute fulminant myocarditis requiring extracorporeal life support (ECLS) are not well-established.

Purpose of the Study:

  • To investigate the survival rates and clinical courses of children with acute fulminant myocarditis who were treated with ECLS.

Main Methods:

  • A retrospective chart review was conducted on 13 consecutive pediatric patients with acute fulminant myocarditis treated with ECLS.
  • Data collected included demographics, symptoms, laboratory results, management strategies, clinical course, and follow-up status.

Main Results:

  • The median age was 25.8 months, and the median body weight was 10.3 kg.
  • The median ECLS duration was 140 hours, with a median intensive care unit stay of 16 days.
  • Twelve out of 13 patients (92.3%) survived to discharge, with most recovering from ventricular dysfunction or undergoing heart transplantation.

Conclusions:

  • Extracorporeal life support (ECLS) can serve as a primary treatment modality for pediatric acute fulminant myocarditis.
  • ECLS demonstrates excellent clinical outcomes and high survival rates in this critically ill pediatric population.
Abstract

Keywords:
ChildrenExtracorporeal life supportMyocarditis

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