Chromosomal aberrations in bone marrow and peripheral blood cells from the same rats
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Updated: Aug 19, 2026
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Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
Published on: February 24, 2014
A K Sinha1, V A Linscombe, B B Gollapudi
1Lake Jackson Research Center, Dow Chemical Company, Freeport, TX 77541.
Mutation Research
|May 1, 1989
Abstract:
Spontaneous cytogenetic aberrations were analyzed in bone-marrow cells and cultured peripheral lymphocytes from the same animals. No significant differences in the total number of cells with aberrations or total aberrations were detected between the bone-marrow cells and cultured lymphocytes. It was concluded that short-term culture does not contribute significantly to in vivo aberration yield within the experimental conditions used.
