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Related Concept Videos

Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Osteoclasts in Bone Remodeling01:31

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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Renal Corpuscle01:20

Renal Corpuscle

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The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
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Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

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Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
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Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Bone Remodeling and Repair01:31

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Related Experiment Video

Updated: Mar 21, 2026

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

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Correction: Bone Canopies in Pediatric Renal Osteodystrophy.

Renata C Pereira, Thomas L Andersen, Peter A Friedman

    Plos One
    |May 12, 2016
    PubMed
    Summary

    This study corrects a previously published article DOI. The correction ensures accurate citation and retrieval of scientific research findings for the scientific community.

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    Area of Science:

    • Bibliometrics
    • Scientific Publishing

    Context:

    • Accurate citation is crucial for scientific integrity.
    • Digital Object Identifiers (DOIs) are essential for locating research.

    Purpose:

    • To correct an erroneous article DOI.
    • To ensure proper referencing of scientific literature.

    Summary:

    • A correction has been issued for the article DOI: 10.1371/journal.pone.0152871.
    • This ensures the DOI accurately links to the intended scientific publication.

    Impact:

    • Improved discoverability of the corrected scientific article.
    • Enhanced reliability of scientific record-keeping and citation practices.