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Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
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A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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Discussion: Managing Risk When Using Idelalisib

Steven E Coutre1, Jan A Burger2, John M Pagel3

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Clinical Advances in Hematology & Oncology : H&O
|May 12, 2016
PubMed
Summary

No abstract available in PubMed .

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