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Implantation of Total Artificial Heart in Congenital Heart Disease
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Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

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Current diagnosis and treatments for critical congenital heart defects

Zhandong Zeng1, Hongwei Zhang1, Fengli Liu1

  • 1Department of Pediatric Surgery, Xuzhou Children's Hospital, Xuzhou, Jiangsu 221002, P.R. China.

Experimental and Therapeutic Medicine
|May 12, 2016
PubMed

Insights

Congenital heart defects (CHD) impact 7% of infants, often linked to the ductus arteriosus. This review covers CHD incidence, risks, diagnosis, and surgical repair options.

Area of Science:

  • Pediatrics
  • Cardiology
  • Medical Genetics

Background:

  • Congenital heart defects (CHD) affect approximately 7% of infants, contributing to 3% of infant mortality.
  • Many CHDs involve the ductus arteriosus, a fetal blood vessel that typically closes after birth.

Purpose of the Study:

  • To review the current incidence of congenital heart defects.
  • To examine risk factors, diagnostic methods, and surgical interventions for CHD.

Main Methods:

  • Literature review of current research on congenital heart defects.
  • Analysis of diagnostic techniques such as pulse oximetry and echocardiograms.
  • Examination of surgical repair options for various CHD types.

Main Results:

  • Identified key risk factors including prematurity, family history, genetic syndromes, in utero infections, and maternal substance use.
  • Detailed common CHD types: Tetralogy of Fallot, Hypoplastic Left Heart Syndrome, Pulmonary Atresia, and others.
  • Summarized diagnostic approaches and current surgical strategies.

Conclusions:

  • Congenital heart defects represent a significant pediatric health concern with identifiable risk factors.
  • Accurate diagnosis and timely surgical intervention are crucial for improving outcomes in infants with CHD.

Keywords:
congenital heart defectspulmonary atresiatricuspid atresiatruncus arteriosus

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