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Updated: Mar 21, 2026

Author Spotlight: Detection and Treatment of Helicobacter pylori Infection
Published on: July 28, 2023
Inappropriate CA 72-4 elevation in a Helicobacter pylori infected patient
Abstract:
Carcinoma antigen 72-4 is a cell surface glycoprotein produced by gastric carcinoma cells. In the case presented, Helicobacter pylori infection induced an inappropriate elevation of this tumour antigen in a 66-year-old female patient, reaching values seen with gastric carcinomas. Extragastric sources of CA 72-4 elevation were ruled out. The elevation slowly returned to normal levels after two courses of triple and sequential eradication therapy, causing considerable anxiety for the patient and several costly examinations.
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