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Updated: Mar 21, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
The Development of Orange Pigment Overlying Choroidal Metastasis
Aline Isabel Riechardt1, Enken Gundlach1, Antonia M Joussen1
1Department of Ophthalmology, Charité Universitätsmedizin, Berlin, Germany.
Aims:
The aim of this study was to correlate the ophthalmoscopic and histopathological findings of orange pigment overlying a choroidal metastasis.
Methods:
This is a single case report with clinical follow-up and histopathological examination.
Results:
Histopathology revealed a choroidal metastasis with subretinal CD68-positive macrophages showing autofluorescent deposits in fluorescence microscopy.
Conclusion:
The development of orange pigment is not pathognomonic for choroidal melanoma but may be seen in other lesions such as carcinoma metastasis.
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