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Notes from the Field: Probable Mucormycosis Among Adult Solid Organ Transplant Recipients at an Acute Care Hospital -

Shannon A Novosad, Amber M Vasquez, Atmaram Nambiar

    MMWR. Morbidity and Mortality Weekly Report
    |May 13, 2016
    PubMed

    Insights

    Health officials investigated a cluster of mucormycosis infections in solid organ transplant recipients at two connected hospitals. The investigation aimed to identify the source and prevent further cases of this rare fungal infection.

    Area of Science:

    • Mycology
    • Infectious Diseases
    • Epidemiology

    Background:

    • Solid organ transplant recipients are immunocompromised and susceptible to opportunistic infections.
    • Mucormycosis is a rare but serious fungal infection caused by molds of the order Mucorales.

    Observation:

    • A cluster of three healthcare-associated mucormycosis cases occurred in transplant recipients over 12 months at Hospital A.
    • An additional case was reported at Hospital B, part of the same healthcare system, shortly after.

    Findings:

    • The investigation focused on identifying potential sources of Mucorales exposure within the connected healthcare facilities.
    • Preventing further transmission among vulnerable transplant patients was a primary objective.

    Implications:

    • Highlights the importance of surveillance for opportunistic infections in immunocompromised patient populations.
    • Emphasizes the need for rapid response and source identification during healthcare-associated outbreaks.
    • Underscores potential risks in connected healthcare facilities serving high-risk patient groups.

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