Related Experiment Video

Updated: Aug 18, 2026

Rapid Genotyping of Animals Followed by Establishing Primary Cultures of Brain Neurons
09:51

Rapid Genotyping of Animals Followed by Establishing Primary Cultures of Brain Neurons

Published on: January 29, 2015

[Pathophysiological mechanisms of torsion dystonia]

V V Skupchenko, L P Bogdanova

    Patologicheskaia Fiziologiia I Eksperimental'Naia Terapiia
    |January 1, 1989
    PubMed

    More Related Videos

    Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia10:05

    Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

    Published on: January 27, 2018

    Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia10:41

    Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia

    Published on: September 12, 2020

    Related Concept Videos

    Torsional Pendulum01:09

    Torsional Pendulum

    A torsional pendulum involves the oscillation of a rigid body in which the restoring force is provided by the torsion in the string from which the rigid body is suspended. Ideally, the string should be massless; practically, its mass is much smaller than the rigid body's mass and is neglected.
    As long as the rigid body's angular displacement is small, its oscillation can be modeled as a linear angular oscillation. The amplitude of the oscillation is an angle. The role of mass is played by the...
    Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin01:26

    Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin

    Directly acting muscle relaxants like dantrolene and botulinum toxin (BoNT) have distinct mechanisms and applications. Dantrolene, a hydantoin derivative, acts on the ryanodine receptor (RYR1) in skeletal muscle cells. RYR1 are calcium channels present at the sarcoplasmic reticulum membrane. In response to excitation, they release calcium ions from the sarcoplasmic reticulum to the cytosol. Calcium promotes actin-myosin-mediated contraction of muscles.
    The binding of dantrolene to the RYR1...
    Torsion in Vector Calculus01:20

    Torsion in Vector Calculus

    A toy train ascending a winding track that curves and tilts offers an intuitive view of torsion, a key geometric concept in the study of space curves. While curvature measures how sharply a path bends, torsion captures how the path twists out of the plane of bending. This twisting behavior is crucial in understanding three-dimensional motion and is precisely described using the Frenet–Serret framework.At each point along a space curve, the Frenet–Serret frame consists of three orthogonal unit...
    Tetanus01:29

    Tetanus

    Tetanus is a life-threatening neurological disorder characterized by persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. These bacteria produce terminal endospores, giving them a distinctive “lollipop” or “tennis-racket” appearance. They thrive in anaerobic environments, such as those found in deep puncture wounds.Once introduced into the body, the spores germinate into vegetative cells. These cells...
    Alterations in Muscle Tone ll01:12

    Alterations in Muscle Tone ll

    Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
    Alterations in Muscle Tone lll01:11

    Alterations in Muscle Tone lll

    Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...