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Related Concept Videos

Thermosensation01:43

Thermosensation

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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Thermal Measurement Techniques in Analytical Microfluidic Devices
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Micro/Nanoscale Thermometry for Cellular Thermal Sensing.

Tingting Bai1, Ning Gu2

  • 1State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, P. R. China.

Small (Weinheim an Der Bergstrasse, Germany)
|May 14, 2016
PubMed
Summary
This summary is machine-generated.

Measuring cell temperature is crucial for understanding life science. Nanotechnology has enabled new cellular thermometers for real-time intracellular temperature monitoring.

Keywords:
cellular temperaturenanotechnologythermometry

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Area of Science:

  • Biophysics
  • Cell Biology
  • Nanotechnology

Background:

  • Cellular temperature is critical for cell function and biochemical reactions.
  • Conventional methods are inadequate for precise intracellular temperature measurement.
  • Understanding cellular thermogenesis requires advanced measurement techniques.

Purpose of the Study:

  • To highlight recent advancements in cellular thermometers.
  • To present applications of these thermometers in cell biology.
  • To discuss the principles, design, and achievements of nanoscale thermometers.

Main Methods:

  • Development of nanotechnology-based thermometers.
  • Real-time intracellular temperature measurement at the micro/nanoscale.
  • High temporal-spatial resolution temperature monitoring.

Main Results:

  • Investigation of thermogenesis mechanisms within cells and organelles.
  • Demonstration of real-time temperature monitoring capabilities.
  • Successful application of novel thermometers in cell biology studies.

Conclusions:

  • Nanotechnology-based cellular thermometers offer high resolution for intracellular temperature measurement.
  • These tools are advancing our understanding of cellular thermogenesis and cell biology.
  • Further opportunities and challenges exist in the development and application of cellular thermometers.