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Association between RASSF1A promoter methylation and renal cell cancer susceptibility: a meta-analysis

Y Q Huang1,2,3, H Guan1,2,3, C H Liu1,2,3

  • 1Department of Urology, Affiliated Zhongda Hospital, Medical School, Southeast University, Nanjing, China.

Genetics and Molecular Research : GMR
|May 14, 2016
PubMed
Summary

Epigenetic silencing of the Ras-associated domain family 1A (RASSF1A) gene through promoter hyper-methylation is linked to increased renal cell cancer risk. This methylation also correlates with higher tumor grade, suggesting its potential in predicting cancer prognosis.

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