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Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...

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Updated: Mar 21, 2026

Isolation of Macrophage Subsets and Stromal Cells from Human and Mouse Myocardial Specimens

Isolation of Macrophage Subsets and Stromal Cells from Human and Mouse Myocardial Specimens

Published on: December 17, 2019

Primitive Macrophages Drive Coronary Development

Clinton S Robbins¹, Rickvinder Besla²

¹From the Peter Munk Cardiac Centre, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada (C.S.R.); and Departments of Laboratory Medicine and Pathobiology (C.S.R., R.B.) and Immunology (C.S.R.), University of Toronto, Toronto, Ontario, Canada. clint.robbins@utoronto.ca.

Circulation Research

|May 14, 2016

Summary

No abstract available in PubMed .

Keywords:

Editorials bone marrow macrophages monocytes yolk sac

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