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Updated: Mar 21, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Modulation of retinal image vasculature analysis to extend utility and provide secondary value from optical coherence
James R Cameron1, Lucia Ballerini2, Clare Langan3
1University of Edinburgh, Anne Rowling Regenerative Neurology Clinic, Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, United Kingdom; University of Edinburgh, Centre for Clinical Brain Sciences, Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, United Kingdom.
Abstract:
Retinal image analysis is emerging as a key source of biomarkers of chronic systemic conditions affecting the cardiovascular system and brain. The rapid development and increasing diversity of commercial retinal imaging systems present a challenge to image analysis software providers. In addition, clinicians are looking to extract maximum value from the clinical imaging taking place. We describe how existing and well-established retinal vasculature segmentation and measurement software for fundus camera images has been modulated to analyze scanning laser ophthalmoscope retinal images generated by the dual-modality Heidelberg SPECTRALIS(®) instrument, which also features optical coherence tomography.

