Related Experiment Video
Updated: Mar 21, 2026

Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
[Immunological background and pathomechanisms of food allergies]
Stefan Schülke1, Stephan Scheurer2
1Molekulare Allergologie, Paul-Ehrlich-Institut, Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel, Paul-Ehrlich-Str. 51-59, 63225, Langen, Deutschland. Stefan.Schuelke@pei.de.
Abstract:
Recent advances in immunology have greatly improved our understanding of the pathomechanisms of food allergies. Food allergies are caused and maintained by complex interactions of the innate and adaptive immune system involving antigen-presenting cells (APC), T cells, group 2 innate lymphoid cells (ILC2), epithelial cells (EC) and effectors cells. Additionally, epigenetic factors, the intestinal microbiome and nutritional factors modulating the gastrointestinal lymphatic tissue probably have a significant impact on allergy development. However, why certain individuals develop tolerance while others mount allergic responses, the factors defining the allergenicity of food proteins, as well as the immunological mechanisms triggering allergy development have yet to be analyzed in detail.
Related Concept Videos
Allergic Reactions
Allergic Drug Reactions
Allergic Reactions: Anaphylaxis
Cross-reactivity
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Drug Toxicity: Allergic Reactions

