Related Experiment Video
Updated: Mar 21, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
Approach behavior and sympathetic nervous system reactivity predict substance use in young adults
J Benjamin Hinnant1, Alissa B Forman-Alberti2, Anna Freedman2
1Auburn University, United States.
Abstract:
A behavioral measure of approach (performance on a resource gathering task) in combination with sympathetic nervous system (SNS) reactivity was used to predict substance use in a sample of young adults (n=93). Pre-ejection period reactivity (PEP-R), a cardiac index of SNS reactivity, was recorded during the resource gathering task (task PEP - resting PEP). Higher levels of approach behaviors on the task in combination with less PEP-R (blunted SNS reactivity) predicted the highest levels of substance use. Findings are discussed in the context of behavioral and physiological systems of approach and avoidance.
More Related Videos
Related Concept Videos
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Drug Abuse and Addiction: Pharmacological Phenomena
Sympathetic Activation
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Drug Dependence
Drugs Affecting Neurotransmitter Release or Uptake

