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Related Concept Videos

Large Intestine01:09

Large Intestine

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Diverticular Disease of the Colon01:27

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Related Experiment Video

Updated: Jul 18, 2026

Surgical Trunk Oriented Laparoscopic Right Hemicolectomy (ST-LRH) for Right-Sided Colon Cancer
05:58

Surgical Trunk Oriented Laparoscopic Right Hemicolectomy (ST-LRH) for Right-Sided Colon Cancer

Published on: July 25, 2025

Right colon cancer: Left behind.

P Gervaz1, M Usel2, E Rapiti2

  • 1Division of Coloproctology, Clinique Hirslanden La Colline, Geneva, Switzerland.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|May 15, 2016
PubMed
Summary

Survival for left-sided colon cancer (CC) has significantly improved, while right-sided CC survival has not. Right-sided CC patients have a worse prognosis, necessitating strategic management changes.

Keywords:
Cancer registryColon cancerLocationPopulation-based studySurvival

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06:46

Caudal-to-cranial Approach in Laparoscopic Right Hemicolectomy with Complete Mesocolon Excision and D3 Lymph Node Dissection

Published on: January 9, 2026

Area of Science:

  • Oncology
  • Epidemiology
  • Cancer Research

Background:

  • Colon cancer (CC) prognosis has improved over three decades.
  • Survival trends may differ between proximal (right) and distal (left) CC.
  • Investigating differential survival improvements based on CC location is crucial.

Purpose of the Study:

  • To determine if survival improvements for colon cancer were greater in left-sided tumors compared to right-sided tumors.
  • To analyze the impact of tumor location on colon cancer outcomes over time.

Main Methods:

  • Utilized data from the Geneva population-based registry (1980-2006).
  • Compared patient, tumor, and treatment characteristics using logistic regression.
  • Assessed CC-specific survival using Cox models, accounting for confounders and changes over time.

Main Results:

  • 3396 CC patients: 39% right-sided, 61% left-sided.
  • Left-sided CC survival improved significantly (HR: 0.42), while right-sided CC survival did not (HR: 0.76).
  • Left-sided CC patients now have a better outcome than right-sided CC patients (HR: 0.81).

Conclusions:

  • Survival for right-sided colon cancer has not improved since 1980, unlike left-sided CC.
  • Right-sided colon cancer presents a significantly worse prognosis.
  • Strategic management changes are warranted for patients with right-sided CC.