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Role of Vitamin D in Cardiovascular Disease
Faezeh Modarresi-Ghazani1, Mohammad Esmaeil Hejazi2, Afshin Gharekhani1
1Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Insights
Vitamin D deficiency is common in cardiovascular disease (CV) patients. While not linked to hypertension, its role in thrombosis requires further research, and it may predict outcomes in coronary artery disease (CAD).
Area of Science:
- Cardiovascular Medicine
- Endocrinology
- Nutritional Science
Background:
- Vitamin D deficiency is prevalent and linked to cardiovascular diseases (CV).
- Beyond skeletal health, vitamin D may reduce risks for hypertension, coronary artery disease (CAD), and thromboembolism.
Purpose of the Study:
- To conduct a comprehensive literature review on the relationship between vitamin D and cardiovascular diseases.
- To synthesize current evidence on vitamin D's impact on hypertension, CAD, and thrombosis.
Main Methods:
- Systematic literature search of PubMed, Scopus, and Google Scholar up to January 2016.
- Inclusion of English-language human studies using keywords: "vitamin D", "blood pressure", "hypertension", "coronary artery disease", and "thrombosis".
Main Results:
- Most studies show no association between vitamin D and hypertension.
- The link between vitamin D and thrombosis remains undetermined.
- Vitamin D shows potential as a predictor of adverse outcomes in coronary artery disease (CAD).
Conclusions:
- A high prevalence of vitamin D deficiency exists in patients with CV diseases.
- Diagnosis and treatment of vitamin D deficiency are crucial for cardiovascular patients.
Background:
According to many studies, vitamin D deficiency has been linked to cardiovascular diseases (CV). Other than maintaining skeletal health, vitamin D has been shown to decrease the risk of developing CV disease such as hypertension, coronary artery disease (CAD) and thromboembolism.
Materials And Methods:
To perform a comprehensive review of the current literature on vitamin D and CV disease, we searched the online database, including PUBMED, Scopus, and Google Scholar until data inception January 2016. The search term included "vitamin D", "blood pressure", "hypertension", "coronary artery disease "and "thrombosis". We only included human studies that were published in English.
Results:
A majority of data indicate that there is no relationship between vitamin D and hypertension, but the association of vitamin D with thrombosis is yet to be determined. Vitamin D is a fair predictor of adverse outcomes in coronary artery disease (CAD), which highlights it for future studies.
Conclusion:
According to research, there is a high prevalence of vitamin D deficiency among patients with CV diseases, which needs to be diagnosed and treated.
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