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Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions

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Pachydermodactyly: A Case Report Including Histopathology.

Schneider K Rancy¹, Richard D Granstein², Manjula Bansal³

¹Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY.

The Journal of Hand Surgery

|May 17, 2016

Summary

Pachydermodactyly (PDD) is a rare fibromatosis causing painless swelling in fingers. This case highlights PDD mimicking inflammatory joint conditions, emphasizing the need for accurate diagnosis.

Keywords:

Pachydermodactyly digital fibromatosis proximal phalanx soft tissue swelling

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Area of Science:

Dermatology
Rheumatology
Pathology

Background:

Pachydermodactyly (PDD) is a rare digital fibromatosis.
It presents as painless soft tissue swelling, predominantly around the proximal interphalangeal joints.
PDD can involve the metacarpophalangeal joints, palm, and dorsum of the hand.

Observation:

PDD swelling near interphalangeal and metacarpophalangeal joints can be mistaken for juvenile inflammatory arthropathy.
PDD may coexist with inflammatory joint conditions.
This report details a case with bilateral proximal phalangeal involvement affecting multiple fingers.

Findings:

Clinical presentation of Pachydermodactyly.
Histopathologic findings in a PDD case.
Bilateral digital fibromatosis affecting index, middle, ring, and little fingers.

Implications:

Accurate differentiation of PDD from inflammatory arthropathies is crucial for appropriate patient management.
Understanding PDD's clinical and histopathologic features aids in diagnosis.
This case contributes to the literature on rare digital fibromatosis presentations.