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Related Experiment Video

Updated: Mar 21, 2026

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
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A New Suturing Device for Small Arteries.

Ryoichi Kondo1, Yoshifumi Itoda, Nirmal Panthee

  • 1Department of Cardiac Surgery, School of Medicine, The University of Tokyo.

International Heart Journal
|May 17, 2016
PubMed
Summary
This summary is machine-generated.

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A novel suturing device simplifies minimally invasive cardiac surgery, significantly reducing operation and suturing times in endoscopic coronary artery bypass grafting procedures. This innovation enhances graft flow compared to conventional methods.

Area of Science:

  • Cardiovascular Surgery
  • Minimally Invasive Techniques
  • Surgical Device Innovation

Background:

  • Endoscope-assisted and robot-assisted surgery are infrequently used in cardiac procedures like coronary artery bypass grafting due to complexity.
  • Conventional suturing methods present challenges in minimally invasive cardiac surgery.

Purpose of the Study:

  • To introduce and evaluate a novel suturing device designed for easier performance of cardiac surgeries.
  • To compare the efficacy of the new device against conventional suturing methods in endoscopic procedures.

Main Methods:

  • A comparative study involving 63 rabbits undergoing right carotid artery bypass grafting under endoscopic guidance.
  • Two groups were established: 48 rabbits operated on with the new device (Group D) and 15 with conventional polypropylene sutures (Group C).

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  • Key metrics including proximal and distal suture times, overall operation time, and graft flow were measured.

    • Main Results:

    • The new device group (Group D) demonstrated significantly shorter proximal suture times (16.6 min vs. 22.8 min) and distal suture times (16.3 min vs. 22.8 min) compared to the control group (Group C).
    • Overall operation time was significantly reduced in Group D (113.0 min) versus Group C (136.7 min).
    • Graft flow was notably higher in Group D (19.9 mL/min) compared to Group C (12.1 mL/min), with all comparisons showing statistical significance (P < 0.05).

    Conclusions:

    • The developed suturing device significantly reduces suture and operation times in endoscopic cardiac surgery.
    • The device offers clear advantages over conventional suturing methods, improving outcomes such as graft flow.
    • This innovation facilitates the broader adoption of minimally invasive techniques in complex cardiac procedures like coronary artery bypass grafting.